What are the two most common surgeries in children with sickle cell disease?

In children with sickle cell disease, the two most common surgeries performed are cholecystectomy and tonsillectomy. Cholecystectomy is often necessary due to the increased risk of gallbladder complications that children with sickle cell disease may experience, such as cholelithiasis (gallstones) and cholecystitis. The abnormal hemoglobin in sickle cell disease can lead to hemolysis and subsequent bilirubin overload, which contributes to gallstone formation.

Tonsillectomy is commonly indicated due to the frequent occurrence of recurrent infections and obstructive sleep apnea in these patients. Tonsillar hypertrophy can lead to airway obstruction and repeated episodes of severe throat infections, necessitating surgical intervention for both breathing improvement and to prevent recurrent health complications.

These surgical procedures are particularly relevant to the management of sickle cell disease complications and underline the need for proactive surgical care in this population.